The first donation is primarily used for testing to ensure the safety and quality your plasma. The first donation can only be used for life-saving medical therapies after a second donation is made, and both donations come back from testing with negative results in accordance with the standards set forth by the Plasma Protein Therapeutics Association (PPTA). Once we have two or more donations, the plasma will be used to produce life-saving therapies. These therapies can provide treatment to patients with conditions such as hemophilia and immune system deficiencies, and to help treat and prevent diseases like tetanus, rabies, measles, hepatitis B, and rubella. In addition, hospitals and emergency rooms all over the world use plasma-derived products to treat injuries such as shock and severe burns. Worldwide, the annual demand for plasma exceeds twenty million liters. It is important to remember that plasma is not a substance that can be synthetically created in a lab. Donors are needed to help supply pharmaceutical companies, hospitals and research facilities with the plasma they need to save lives.