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Frequently Asked Questions

What is plasma?

Blood is made up of four main components: red blood cells, white blood cells, platelets, and plasma. Plasma is the yellow, liquid portion of blood that serves as the carrier for cells and other minor blood components. Plasma is primarily composed of water and is needed for its dissolved proteins, clotting factors, and various antibodies.

Do I need to provide a negative COVID-19 test or antibody results to donate plasma? 
B Positive Plasma continues collects both regular source plasma and convalescent COVID-19 plasma from individuals that have fully recovered from a COVID-19 infection.

If you want to donate plasma and are feeling healthy and well and have not been exposed to a COVID-19 infection, you may register to donate regular source plasma. You DO NOT need to provide any documentation regarding COVID-19 to donate plasma. The need for plasma to create life-saving medical therapies extends beyond the current need for COVID-19. If you are feeling well and healthy and meet the criteria to donate plasma, we strongly encourage you to do so!
If you recovered from a COVID-19 infection and you wish to donate convalescent COVID-19 plasma, you are required to provide specific documentation. Learn more about our Convalescent COVID-19 Plasma program here.

Donors are issued a reloadable B Positive Visa Debit card at their first donation. All compensation, including referral bonuses, are then paid to your B Positive Visa Debit card. This card can be used anywhere Visa is accepted. It can be used as credit, debit, and at ATMs.

To view our current compensation and bonus programs, please click here.

There are 5 free ways to check your balance:

1) Swipe your card at the kiosk located in your B Positive Plasma center lobby

2) Sign up for text message alerts, text “JOIN” to 33433

3) Call 877-430-3628

4) Register for an account at www.mypaysign.com

5) Download the Paysign App in the Apple or Google Apps stores

To earn a referral bonus you must be a qualified donor and complete at least 2 successful donations. Referral bonuses are paid within 3 business days (Mon - Fri) of the new donor’s second complete donation. All referral bonuses are paid to your B Positive Visa Debit card.  To view our current referral bonus incentive, please click  here .

Please note: only one payment transaction is payable per B Positive Plasma Visa loyalty card per day. If you receive a referral bonus your donation payment for that day will be payable the following day. Only one referral is payable per day. If 2 are payable the same day, the second one will be paid the following day. 

Donors must:

  • Be between the ages of 18 and 65. Donors become ineligible as of their 66th birthday.
  • Weigh between 110 and 400 pounds
  • Live near their B Positive Plasma center — within 50 miles of our Cherry Hill and Glassboro centers or 35 miles of our College Park center

First-time donors* must provide the following documentation:

  • Valid government-issued photo ID (cannot be expired)
  • Original Social Security Card or an acceptable alternative
  • Proof of current address within 50 miles of our Cherry Hill and Glassboro centers or 35 miles of our College Park center

Eligibility to participate in our program is determined during your first donation appointment. Select a center and schedule an appointment to get started.

*This information is also required if you have not donated at B Positive Plasma in 6 months or longer.

All first-time donors must present the following documentation to register as a donor at B Positive Plasma. If you have questions about the required documentation, pleasecontact usprior to scheduling an appointment

  •  A valid, current (not expired) government or state-issued photo identification such as a driver’s license, residency card, or passport.

    • Your photo ID cannot be expired. Please double check the expiration date on your ID prior to scheduling your first donatinon.

  • An original Social Security Card (SSC)

    • Effective 6/22/20 - we can now accept both original and copies of SSCs. If you do not have either your original SSC or a copy, you must provide one of the following as an alternatite proof of your full nine digit Social Security Number (SSN). We cannot accept any documents that only dislay a partial SSN.

      • A tax document such as a W2, 1099 or 1040 that contains your full legal name and SSN

      • An official school transcript or student loan document that contains your full legal name and SSN

      • A bank document or loan document that contains your full legal name and SSN

      • A court document or other legal document that contains your full legal name and SSN

  • Proof of your Current Address within 50 miles of a B Positive Plasma location*

    • We verify your location using Google Maps, your address must be equal to or less than 50.0 miles from our location in Google Maps to be eligible. Donors must provide proof of a permanent, residential address. PO Boxes are not acceptable.

    • If your current address is not on your photo ID, you must bring one of the following documents that contains your full name and current address:

      • A current mortgage statement or lease dated within 90 days. Electronic documents are acceptable. 

      • A bank statement or paystub dated within 90 days. Electronic documents are acceptable. 

      • Other government-issued documentation, including from the judiciary, dated within 90 daysElectronic documents are acceptable. 

      • A utility bill that contains your full name and address dated within 60 days. Electronic documents are acceptable. 

      • A personal bill (cell phone, medical, etc.) that contains your full name and address and is dated within 60 days. Electronic documents are acceptable. 

      • Personal mail with a postmarked envelope that contains your full name and address and is dated within 60 days. Electronic documents are notacceptable.

*Some exceptions may apply to the donor residence proximity requirement, such as being a college student,  being military personnel or convalescent COVID-19 donors. Contact us if you have questions about documentation or eligibility. Documentation requirements are subject to change. 

If you previously donated at B Positive Plasma and are returning after a gap of more than 4 months, you are required to bring only a photo ID and proof of your current address. Contact us if you are interested in returning to our program for instructions. 

All donor information is safely secured at all times. All test results are kept strictly confidential, unless the donor gives permission to share them or we are required to do so by law. Donors will be notified by our management team or medical professionals regarding the finding of any adverse test results.

Drink 8-10 glasses of water per day to ensure you are well-hydrated. Eat a well-balanced meal within two hours of your donation appointment. Avoid fatty, greasy foods and significant amounts of dairy. You will not be compensated for fatty donations of plasma, though fatty donations can easily be avoided with a healthy diet. Maintaining a healthy diet and drinking plenty of non-caffeinated, non-alcoholic beverages the day before and the day of donating is very important. Prior to your donation, we recommend avoiding strenuous exercise, alcohol consumption, and smoking.

To ensure the safety of the plasma supply, every donation is tested for hepatitis and HIV. Periodic tests for syphilis, atypical antibodies, and other abnormalities are also performed.  To keep our donors healthy, every time they visit our center to donate we test their protein and red blood cell levels (hematocrit), along with their blood pressure, pulse, weight, and temperature. There is also an external lab test of our donors’ protein levels after their first donation and periodically thereafter, as required by law.  Please note that it is common for the external lab and internal protein tests to differ in value, and either test may result in a temporary deferral from donating.

All test results are kept strictly confidential unless the donor gives permission to share it or we are required to do so by law. Donors will be notified by our management team or medical professionals regarding the finding of any adverse test results. B Positive Plasma does not test for blood type.

The first donation is primarily used for testing to ensure the safety and quality of your plasma.  Your first donation can only be used for life-saving medical therapies after a second donation is made, and both donations come back from testing with negative results in accordance with the standards set forth by the Plasma Protein Therapeutics Association (PPTA).

Once we have two or more donations, the plasma will be used to produce life-saving therapies. These therapies can provide treatment to patients with conditions such as hemophilia and immune system deficiencies, and help treat and prevent diseases like tetanus, rabies, measles, hepatitis B, and rubella. In addition, hospitals and emergency rooms all over the world use plasma-derived products to treat injuries such as shock and severe burns. Worldwide, the annual demand for plasma exceeds twenty million liters. It is important to remember that plasma is not a substance that can be synthetically created in a lab. Donors are needed to help supply pharmaceutical companies, hospitals and research facilities with the plasma they need to save lives.

Whole blood donation and plasma donation meet very different needs in the community and medical world. Donating whole blood involves the collection of red blood cells, in addition to plasma and platelets. Whole blood donors can only donate one pint of blood every 56 days in accordance with FDA guidelines.


Donating plasma involves removing and keeping the liquid component of blood while returning the red blood cells and other blood components back to the donor’s body using a specialized process called plasmapheresis. The process of donating plasma does take longer because blood components must be separated and returned to the body in a few cycles. This is why donors are capable of donating more frequently – plasma donors can donate as often as twice a week (but not two days in a row), whereas whole blood donors can only donate once every 56 days (or 128 days if they did a double red cell donation).

After your donation, we recommend drinking plenty of fluids and eating a snack or light meal. Avoid smoking cigarettes and consuming alcohol after your donation. Keep the needle site clean and dry and keep the bandage on for at least 2-3 hours. If bleeding persists, raise your arm above your heart and apply pressure. If fainting or dizziness occurs, lie down and ask someone to give you a cold beverage (non-diet sodas and juices are best) and place a cool towel on your neck and forehead. If any symptoms persist, contact our facility and ask to speak with a member of our medical personnel. If one or more symptoms are severe, you should seek professional medical attention as soon as possible.

According to regulations, individuals who are pregnant cannot donate plasma. Women are allowed to donate again 6 months after giving birth, with medical clearance.

Select a location and schedule your first donation appointment online! First-time donors are encouraged to make an appointment. The acceptance of walk-in first-time donors is based on availability. Repeat donors do not have to make an appointment to donate, and can just walk-in during normal business hours.

Donating plasma is similar to donating blood. A donor will be comfortably reclined in a chair during the actual donation. A needle is placed in one arm and the blood goes through specialized plasmapheresis equipment that separates your plasma from the rest of the blood components. A donor’s red blood cells are then returned to the body using the same needle. All materials that come into contact with a donor’s blood during the plasmapheresis process are sterile and single-use only. During your donation, you will have the use of one arm and may use a handheld device or just relax and watch TV.  Learn more about the plasma donation process.

You can donate plasma up to 2 times in a 7 day period, with at least 1 day between donations.  If you have questions about when you are eligible to donate again, we encourage you to contact us prior to coming into our center.

B Positive Plasma reserves the right to not allow someone to donate plasma at any time

Thousands of people safely donate plasma every day. All of the materials that come in contact with each donor’s blood are sterile, opened in the donor’s presence, and used only once before being disposed of. The equipment that is used to collect the donor’s plasma never comes into contact with the donor’s blood. Donor safety is our number one priority and we aim to meet or exceed all applicable regulatory requirements.

We accept all blood types! You do not need to know your blood type to participate.  Please note that B Positive Plasma does not test for blood type.

B Positive donors are financially compensated for the time they spend donating blood plasma. You can view our current Donor Promotions here.  Qualified donors are eligible to donate up to twice a week and can receive an average of $50 per week in the form of a reloadable B Positive Visa debit card*. Make more money and save more lives when you refer friends to donate at B Positive Plasma.

*B Positive reserves the right to not allow an individual to donate twice in one week for any reason at any time.

Please note: only one payment transaction is payable per B Positive Plasma Visa loyalty card per day. If you receive a referral bonus your donation payment for that day will be payable the following day. Only one referral is payable per day. If 2 are payable the same day, the second one will be paid the following day. 

Our main goal is to ensure the safety of our donors and the blood products that they donate. Prospective donors are required to visit our center to speak with a member of our medical staff to assess their eligibility. During the screening process, we will evaluate your medical history and any medications that you are taking to determine your eligibility to donate. Unfortunately, we are unable to assess your overall health status and donor eligibility remotely.