The Donation Process - B Positive Plasma

The Donation Process

Your plasma is collected through a special process that separates your plasma from whole blood when you donate at B Positive Plasma. Interested in learning more or have some questions about it? B Positive Insider will help with the answers. 


Can you provide more details on the process? 

The process by which plasma is separated from whole blood is called plasmapheresis. The process is similar to whole blood donation; however, your tubing is connected to a machine that spins and separates the liquid portion of your blood from red and white blood cells and platelets. Your plasma then flows into a collection bottle and the other components are returned back to you.  

Is it safe? 

Your safety is our number one priority! Plasmapheresis is an automated process that is safe and used in more than 600 plasma donation centers across the U.S. and Europe. All of the supplies that products we use during your donation are single use and opened in front of you. All of our procedures and equipment are designed with your safety in mind.  

How long will the process take? 

Once you are connected to a plasmapheresis machine, your donation will take an average of 45 minutes. The process may take longer depending on proper nutrition and hydration.  

Does it hurt? 

You will feel a slight pinch upon needle stick, however, the process should not be painful. It depends on you pain tolerance, but donors rarely experience discomfort during their donation. If you feel discomfort during your donation, please let a phlebotomist know. 

What can I do while I donate? 

Donors are encouraged to relax on the bed and use their phones, read, watch TV, listen to music, or chat with other donors during the process. The beds also have charging stations and the center has free WiFi!

Still interested in earning a total of $250 your first 5 donations and saving a life by giving blood plasma? Get started at!   



Plasma Protein Therapeutics Association. "Donating Plasma". Accessed: January 2, 2018. Retrieved from: 


Get lucky in March with B Positive Plasma's 7th anniversary promotions! There's 3 bonus weeks, a $100 loyalty reward when you complete your 7th donation, and you can earn $35 for EVERY FIRST-TIME DONOR YOU REFER when they include your full name when they sign up online! There is no limit to how many friends you can refer, but hurry because this amount is a LIMITED-TIME OFFER that expires 3/31! 

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