How does source plasma help save lives, exactly? - B Positive Plasma

How does source plasma help save lives, exactly?

Hi there, it’s your B Positive Insider here to let you know about ways you help further scientific progress and the creation of life-saving medical therapies by donating blood plasma! It’s truly marvelous that you are saving lives through donations, and I want you to KNOW!


The plasma you donate through plasmapheresis at B Positive Plasma is frozen on-site then shipped to a laboratory and broken down into component parts to be further manufactured into life-saving therapies, a process called fractionation. I’ll delve into medical therapies deeper in a different post, but there are four types of source plasma products, and they are:

     1. Immune globulins (IgG)

Immune globulins are generated by B-cells in the body and are necessary to fight off infection by destroying foreign viral and bacterial molecules. There are two kinds of IgG therapies created with source plasma: intravenous and subcutaneous immunoglobulins (IVIG) and hyperimmune immunoglobulins. The former increases immune globulins in people with diseases like Kawasaki Disease and Chronic Lymphocytic Leukemia, and the latter targets specific antigens in the bodies of people with diseases like Hepatitis A and B.


       2. Hemophilia

People with hemophilia lack the necessary clotting factor in their blood and experience excessive bleeding when they get even a small cut, so they are unable to control bleeding without a replacement protein therapy. That’s where source plasma comes in.

      3. Albumin

Albumin is a replacement therapy for blood or fluid loss, and can be used during surgery or trauma situations when a patient experiences sepsis, septic shock, therapeutic plasma exchange, and other emergencies.


       4. Alpha-1 antitryspin (AAT) or Alpha-1 Protease Inhibitor (A1P1)

This is a replacement therapy for people suffering reduced serum levels of the A1P1 enzyme, a rare genetic condition. If left untreated, people with this disorder are susceptible to emphysema, neonatal hepatitis, chronic obstructive pulmonary disease, and more.


In short, you are giving the gift of LIFE to some people! Our donors are eligible for compensation because their plasma is used for this purpose and not for transfusion; donating plasma to be used in emergency services is an unpaid volunteer act. However, this doesn’t mean that source plasma products aren’t used in emergencies: burn victims and patients in need of bone marrow transplants may receive them.


Carter BloodCare. (2016, April 5). “Everything you need to know about source plasma”. Retrieved from:

Marketing Research Bureau. (2017, July 28). “Clinical uses of source plasma products”. Retrieved from:

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